Syntheses and Facile Cleavage of Five-Membered Ring Sultams1

WF Erman, HC KRETSCHMAR

Index: Erman,W.F.; Kretschmar,H.C. Journal of Organic Chemistry, 1961 , vol. 26, p. 4841 - 4850

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Citation Number: 23

Abstract

Five-membered N-alkylsultams (I), prepared from the corresponding,\--alkylpropane sultainee, RKH&HZCH~ CH~ SO~@(11) or 3-bromopropanesulfonamides, BrCH&HRCH&O* NHR (VII), were cleaved rapidly, at room temperature and below, by methanolic or ethereal hydrogen bromide or hydrogen chloride solution, and at 118'by acetic acid. In methanol or acetic acid the products of sultam cleavage were the ...