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Syntheses and Facile Cleavage of Five-Membered Ring Sultams1

WF Erman, HC KRETSCHMAR

文献索引:Erman,W.F.; Kretschmar,H.C. Journal of Organic Chemistry, 1961 , vol. 26, p. 4841 - 4850

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被引用次数: 23

摘要

Five-membered N-alkylsultams (I), prepared from the corresponding,\--alkylpropane sultainee, RKH&HZCH~ CH~ SO~@(11) or 3-bromopropanesulfonamides, BrCH&HRCH&O* NHR (VII), were cleaved rapidly, at room temperature and below, by methanolic or ethereal hydrogen bromide or hydrogen chloride solution, and at 118'by acetic acid. In methanol or acetic acid the products of sultam cleavage were the ...