Impairment of myocardial contractility by anticancer anthracyclines: role of secondary alcohol metabolites and evidence of reduced toxicity by a novel …

G Minotti, M Parlani, E Salvatorelli…

Index: British Journal of Pharmacology, , vol. 134, # 6 p. 1271 - 1278

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Citation Number: 32

Abstract

... A combination of reduced uptake and limited conversion to alcohol metabolite formation might therefore render MEN 10755 more cardiac tolerable than DOX and EPI. British Journal of Pharmacology (2001) 134, 1271–1278; doi:10.1038/sj.bjp.0704369. ... J. Natl. ...