Interindividual variability in expression and activity of human β-glucuronidase in liver and kidney: consequences for drug metabolism

B Sperker, TE Mürdter, M Schick, K Eckhardt…

Index: Journal of Pharmacology and Experimental Therapeutics, , vol. 281, # 2 p. 914 - 920

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Citation Number: 50

Abstract

... In addition, some glucuronic acid metabolites have direct pharmacological activity (for review see Kroemer and Klotz, 1992), the most prominent example being the analgesic effects that follow the administration of ... Brater DC. (1988) Clinical pharmacology of NSAIDs. ... J. Inher. ...