Synthesis and antibacterial activity of conjugates between norfloxacin and analogues of the siderophore vanchrobactin

…, CR Osorio, J Rodríguez, ML Lemos, C Jiménez

Index: Souto, Alba; Montaos, Marcos A.; Balado, Miguel; Osorio, Carlos R.; Rodriguez, Jaime; Lemos, Manuel L.; Jimenez, Carlos Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 1 p. 295 - 302

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Citation Number: 12

Abstract

From synthetic functionalized analogues of vanchrobactin, a siderophore produced by the fish pathogenic bacteria Vibrio anguillarum serotype O2, several vanchrobactin analogues– norfloxacin conjugates were obtained and their antimicrobial activities against the wild-type and mutant strains of Vibrio anguillarum serotype O2 have been determined.