Abstract In this study, novel series of chalcone derivatives, namely, 4-[4-(3-phenyl-acryloyl)- phenylamino]-chromen-2-one (5a–k) have been synthesized from the intermediate 4-(4- acetyl-phenylamino)-chromen-2-one (4). Cyclization reaction of chalcone (5a–k) with hydrazine hydrate, guanidine nitrate, and malononitrile gives the corresponding 4-[4-(1- acetyl-5-phenyl-4, 5-dihydro-1 H-pyrazol-3-yl)-phenylamino]-chromen-2-one (6a–k), 4-[4-( ...
