Journal of Fluorine Chemistry

Fluorine containing heterocyclic compounds: synthesis of 6-substituted-2-substituted-aryl-1, 2, 4-triazolo [5, 1-b] 1, 3, 5-thiadiazin-7-one derivatives

S Liu, X Qian, G Song, J Chen, W Chen

Index: Liu, Suyou; Qian, Xuhong; Song, Gonghua; Chen, Jing; Chen, Weidong Journal of Fluorine Chemistry, 2000 , vol. 105, # 1 p. 111 - 115

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Citation Number: 15

Abstract

A group of heterocylic compounds of condensed triazole-thiadiazinone derivatives containing fluorine (IIIa–h) were obtained in good yields by the reactions of the corresponding 3-aryl-5-mercapto-1, 2, 4-triazole (IIa–d) with N-substituted-N-chloromethyl carbamoyl chloride (I) in the presence of potassium carbonate in N, N-dimethylformamide at room temperature. Cyclization of 3-(2, 3, 5-trifluoro-4-methoxyl) phenyl-5-mercapto-1, 2, 4- ...