e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

An asymmetric approach to coumarin anticoagulants via hetero-Diels–Alder cycloaddition

G Cravotto, GM Nano, G Palmisano…

Index: Tetrahedron Asymmetry, , vol. 12, # 5 p. 707 - 709

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Citation Number: 151

Abstract

... Tetrahedron: Asymmetry. Volume 12, Issue 5, 2 April 2001, Pages 707–709. Cover image Cover image. ... and 11. or to the dienophile. 12. and 13. ... Accordingly, the endo-mixture was dissolved in the minimum volume of EtOAc and diluted with twice the volume of di-iso-propyl ether. ...

4-Hydroxycoumarin Structure

4-Hydroxycoumarin

4-Chlorobenzaldehyde Structure

4-Chlorobenzaldehyde

isopropenyl (-)-(1R,2S,5R)-menthol ether Structure

isopropenyl (-)...

~%

COUMACHLOR Structure

Detail

4-Hydroxycoumarin Structure

4-Hydroxycoumarin

2-methyoxypropene Structure

2-methyoxypropene

Benzaldehyde Structure

~%

Warfarin Structure

4-Hydroxycoumarin Structure

4-Hydroxycoumarin

~%

acenocoumarol Structure

4-Nitrobenzaldehyde Structure

4-Nitrobenzaldehyde

~%

acenocoumarol Structure

Atom??Economic Synthesis of Optically Active Warfarin Antico...

[Advanced Synthesis and Catalysis, , vol. 355, # 13 p. 2538 - 2543]

Highly enantioselective synthesis of warfarin and its analog...

[Tetrahedron, , vol. 66, # 51 p. 9708 - 9713]

Retention and selectivity of teicoplanin stationary phases a...

[Analytical Chemistry, , vol. 73, # 22 p. 5499 - 5508]

Organocatalytic Asymmetric Michael Reaction of Cyclic 1, 3??...

[Angewandte Chemie - International Edition, , vol. 42, # 40 p. 4955 - 4957]