Chemoselective Reactions of Tellurium Tetraethoxide towards Thioamides and Amides.

K Omote, Y Aso, T Otsubo, F Ogura

Index: Omote, Kazushi; Aso, Yoshio; Otsubo, Tetsuo; Ogura, Fumio Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 6 p. 1759 - 1761

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Abstract

Tellurium tetraethoxide reacts with primary thioamides at room temperature, forming nitriles in high yields. On the other hand, the reactions with amides are largely temperature- dependent, giving predominantly esters at 80° C and nitriles at a higher temperature. Similarly, tellurium tetraethoxide readily induces the C–N bond cleavage of ureas to give carbamates and amines.