Syntheses of antibacterial 2, 4-diamino-5-benzylpyrimidines. Ormetoprim and trimethoprim

PS Manchand, P Rosen, PS Belica…

Index: Journal of Organic Chemistry, , vol. 57, # 13 p. 3531 - 3535

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Citation Number: 23

Abstract

... The mixture was stirred at 60 "C for 17 h, cooled to (OCH3). 55.80 (OCHa), 111.24 (CHI, 112.40 (CH), 120.76 (CH), J. Org. Chem., Vol. 57, No. 13, 1992 3633 (9) Hartman, WW; Brethen, MR Organic Syntheses; Wiley: New York, 1941; Collect. Vol. 1, p 162. ...