Selective Cyclodimerization and Cyclotrimerization of Acetals Bearing Electron??Withdrawing Groups Catalyzed by Lewis Acids

S Maeda, Y Obora, Y Ishii

Index: Maeda, Sayuki; Obora, Yasushi; Ishii, Yasutaka European Journal of Organic Chemistry, 2009 , # 24 p. 4067 - 4072

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Citation Number: 3

Abstract

Abstract Acetals like 3, 3-diethoxypropionate bearing electron-withdrawing groups were found to undergo cyclodimerization and cyclotrimerization in the presence of Lewis acids to give coumalates and 1, 3, 5-trisubstituted benzenes. The selectivity of these products depended on the Lewis acids employed. For instance, ethyl coumalate was obtained from ethyl 3, 3-diethoxypropionate in high selectivity under the influence of d-block Lewis acids ...