'Measured in 1-2% amino acids, such as tryptophan, are hardly esterified in a strongly acidic medium and at high temperature. In 1963, Wilchek et al. e synthesized tryptophan benzyl ester via N-carboxy anhydride with phosgene, followed by treatment of the intermediate with benzyl alcohol. Recently, Williams et al. 1 reported the preparation of tryptophan benzyl ester by the thermal decomposition of a benzyldimethylanilinium salt of N-protected ...
