A Facile and Efficient Oxalyldihydrazide/Ketone??Promoted Copper??Catalyzed Amination of Aryl Halides in Water

X Zhu, L Su, L Huang, G Chen, J Wang…

Index: Zhu, Xinhai; Su, Li; Huang, Liye; Chen, Gong; Wang, Jinlong; Song, Huacan; Wan, Yiqian European Journal of Organic Chemistry, 2009 , # 5 p. 635 - 642

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Citation Number: 34

Abstract

Abstract A novel three-component catalyst CuO/oxalyldihydrazide/hexane-2, 5-dione was a very convenient, economic, and effective catalytic system for the Ullmann-type C–N coupling reaction in water. Both aryl bromides and aryl iodides could be aminated by a variety of amines even at room temperature or with heating to afford very good isolated yields.(© Wiley- VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

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