Heck Reactions of α??or β??Substituted Enol Ethers with Aryl Bromides Catalysed by a Tetraphosphane/Palladium Complex–Direct Access to Acetophenone or 1?? …

A Battace, M Feuerstein, M Lemhadri…

Index: Battace, Ahmed; Feuerstein, Marie; Lemhadri, Mhamed; Zair, Touriya; Doucet, Henri; Santelli, Maurice European Journal of Organic Chemistry, 2007 , # 19 p. 3122 - 3132

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Citation Number: 11

Abstract

Abstract cis, cis, cis-1, 2, 3, 4-Tetrakis (diphenylphosphanylmethyl) cyclopentane/[PdCl (C 3 H 5)] 2 efficiently catalyses the Heck reaction of α-and β-substituted enol ethers with aryl bromides. The arylation of 1-phenyl-1-(trimethylsilyloxy) ethylene led directly to the 2-aryl-1- phenylethanones. Similar reaction rates were observed with electron-rich, electron-deficient or sterically congested aryl bromides. Heck reaction with benzyl isopropenyl ether gave a ...