Fast and highly chemoselective alkynylation of thiols with hypervalent iodine reagents enabled through a low energy barrier concerted mechanism

R Frei, MD Wodrich, DP Hari, PA Borin…

Index: Huang, Hanchu; Zhang, Guojin; Gong, Li; Zhang, Shuaiyan; Chen, Yiyun Journal of the American Chemical Society, 2014 , vol. 136, # 6 p. 2280 - 2283

Full Text: HTML

Citation Number: 55

Abstract

... Journal of the ... 2014, 136 (47), pp 16563–16573. DOI: 10.1021/ja5083014. Publication Date (Web): November 1, 2014. Copyright © 2014 American Chemical Society. ... vinyl benziodoxolone 6 could be observed, although the small quantities of 6 formed did not allow us to isolate ...

~90%

~95%

~91%

Copper-catalyzed decarboxylative coupling of aryl halides wi...

[Li, Tingyi; Sun, Peng; Yang, Hailong; Zhu, Yan; Yan, Hong; Lu, Linhua; Mao, Jincheng Tetrahedron, 2012 , vol. 68, # 32 p. 6413 - 6419]

Palladium-catalyzed R (sp3)-Zn/R (sp)-SnBu3 oxidative cross-...

[Jin, Liqun; Zhao, Yingsheng; Wang, Haibo; Lei, Aiwen Synthesis, 2008 , # 4 p. 649 - 654]

Iron??Catalyzed Cross??Coupling between 1??Bromoalkynes and ...

[Castagnolo, Daniele; Botta, Maurizio European Journal of Organic Chemistry, 2010 , # 17 p. 3224 - 3228]

Iron??Catalyzed Cross??Coupling between 1??Bromoalkynes and ...

[Castagnolo, Daniele; Botta, Maurizio European Journal of Organic Chemistry, 2010 , # 24 p. 4732 - 4732]

Titanium??Mediated Carboxylation of Alkynes With Carbon Diox...

[Six, Yvan European Journal of Organic Chemistry, 2003 , # 7 p. 1157 - 1171]