Microwave??Assisted Convenient Synthesis of α, β??Unsaturated Esters and Ketones via Aldol??Adduct Elimination

…, R Nageswara Rao, B China Raju

Index: Suman, Pathi; Nageswara Rao, Rayala; China Raju, Bhimapaka Helvetica Chimica Acta, 2013 , vol. 96, # 8 p. 1548 - 1559

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Citation Number: 5

Abstract

Abstract Various fluorinated 3-oxo ester/1, 3-diketones were reacted with carbonyl compounds, in presence of piperidine and under microwave irradiation, to afford (E)-α, β- unsaturated esters and ketones in good yields. The systematic study reveals that the reaction proceeded through the formation of aldol adduct. The method provides a new and simple way for C, C bond formations.