Tetrahedron Letters

Palladium bis (2, 2, 6, 6-tetramethyl-3, 5-heptanedionate): an efficient catalyst for regioselective C-2 arylation of heterocycles

NS Nandurkar, MJ Bhanushali, MD Bhor…

Index: Nandurkar, Nitin S.; Bhanushali, Mayur J.; Bhor, Malhari D.; Bhanage, Bhalchandra M. Tetrahedron Letters, 2008 , vol. 49, # 6 p. 1045 - 1048

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Citation Number: 66

Abstract

Palladium bis (2, 2, 6, 6-tetramethyl-3, 5-heptanedionate), a structurally well defined O- containing transition metal complex is reported as an efficient catalyst for regioselective direct C-2 arylation of heterocycles with aryl halides. The present protocol is applicable to a wide variety of heterocycles providing good to excellent yields of products.