The Journal of Organic Chemistry

Ylide-carbene chemistry. Synthesis of 1, 1-difluoro-1-alkenes

GA Wheaton, DJ Burton

Index: Wheaton, Gregory A.; Burton, Donald J. Journal of Organic Chemistry, 1983 , vol. 48, # 7 p. 917 - 927

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Citation Number: 47

Abstract

The reaction between nonstabilized alkylidenetriphenylphosphoranes and chlorodifluoromethane has been found to be a useful alternative to the Wittig reaction for the synthesis of many difluoromethylene olefins. Both primary and secondary ylidea which do not contain strongly electron-withdrawing substituents within the alkylidene portion of the ylide react with chlorodiiuoromethane to give the corresponding difluoromethylene olefins ...