Synthesis

Synthesis of substituted 2, 2′-bipyridines from 2-bromo-or 2-chloropyridines using tetrakis (triphenylphosphine) palladium (0) as a catalyst in a modified Negishi …

U Kiehne, J Bunzen, H Staats, A Lützen

Index: Kiehne; Bunzen; Staats; Luetzen Synthesis, 2007 , # 7 p. 1061 - 1069

Full Text: HTML

Citation Number: 18

Abstract

Abstract A protocol for an efficient, modified Negishi cross-coupling strategy for substituted 2, 2′-bipyridines employing tetrakis (triphenylphosphine) palladium (0) as a simple, commercially available, and relatively inexpensive catalyst for both 2-bromo-and 2- chloropyridines has been developed. Further transformations were carried out yielding some new valuable functionalized 2, 2′-bipyridines.