Haplophytine (1, Figure 1) is an architecturally intriguing and synthetically daunting heterodimeric alkaloid endowed with insecticidal properties. Originally isolated in 1952 by Snyder and co-workers [1a–d] from the Mexican plant Haplophyton cimicidum, the structure of haplophytine was finally revealed in 1973 as a result of the pioneering studies of the groups of Cava,[1e, h] Yates,[1f, h] and Zacharias.[1f, g] The haplophytine molecule ...
![Butanoic acid,4-[[2-(1H-indol-3-yl)ethyl]amino]-4-oxo-, methyl ester Structure](https://image.chemsrc.com/caspic/176/92870-51-4.png)