Parallel synthesis and yeast growth inhibition screening of succinamic acid libraries

P Serrano, J Casas, A Llebaria, M Zucco…

Index: Tomori, Hiroshi; Maruyama, Hiroshi; Ogura, Katsuyuki Heterocycles, 1996 , vol. 43, # 2 p. 415 - 423

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Citation Number: 12

Abstract

... solvent was removed under reduced pressure, and Amberlyst15 was added manually to each plate, followed by a fixed volume of MeOH. ... The acetate hydrolysis of libraries 1−5 (see Scheme 2) was very efficient because the average purities of the resulting ... 7{44}, 44, 10{48}, 43. ...