Letters in Organic Chemistry

Synthesis of Novel Succinic Acid Derivatives as Potential Matrix Metalloproteinases Inhibitors and Anticancer Medicine

H Huang, D Chen, S Li, C Liu

Index: Huang, Huiming; Chen, Dan; Li, Shaohua; Liu, Chengmei Letters in Organic Chemistry, 2010 , vol. 7, # 2 p. 155 - 158

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Abstract

In this paper we have designed different methods, according to the differences in nucleophilicity of amino, to conjugate tartaric acid or malic acid with two kinds of useful intermediates respectively via amide bond, envisaging they are promising matrix metalloproteinase inhibitors or anticancer medicine.