Lewis Base??Catalyzed Addition of Trialkylaluminum Compounds to Epoxides

C Schneider, J Brauner

Index: Schneider, Christoph; Brauner, Joerg European Journal of Organic Chemistry, 2001 , # 23 p. 4445 - 4450

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Citation Number: 22

Abstract

Abstract A novel concept for catalytic epoxide alkylation has been developed. Lewis bases like phosphanes, arsanes, stibanes, and sulfides were found to catalyze the alkylation of symmetrical epoxides with trialkylaluminum compounds very effectively at a 5 mol% level. Cyclic as well as acyclic epoxides were readily alkylated in good yields. In reactions with terminal epoxides a significant enhancement of rate and/or regioselectivity was noted in ...