Lewis Base??Catalyzed Addition of Trialkylaluminum Compounds to Epoxides

C Schneider, J Brauner

文献索引：Schneider, Christoph; Brauner, Joerg European Journal of Organic Chemistry, 2001 , # 23 p. 4445 - 4450

全文：HTML全文

被引用次数: 22

摘要

Abstract A novel concept for catalytic epoxide alkylation has been developed. Lewis bases like phosphanes, arsanes, stibanes, and sulfides were found to catalyze the alkylation of symmetrical epoxides with trialkylaluminum compounds very effectively at a 5 mol% level. Cyclic as well as acyclic epoxides were readily alkylated in good yields. In reactions with terminal epoxides a significant enhancement of rate and/or regioselectivity was noted in ...