Biosynthesis of vitamin B1 in yeast. Derivation of the pyrimidine unit from pyridoxine and histidine. Intermediacy of urocanic acid

J Zeidler, BG Sayer, ID Spenser

Index: Furuta, Takashi; Katayama, Motofusa; Shibasaki, Hiromi; Kasuya, Yasuji Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 13 p. 1643 - 1648

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Citation Number: 45

Abstract

... Journal of the ... on the origin of thiamin in yeast were carried out by incubations with 14 C-labeled substrates, followed by chemical degradation of ... A chemically rational process, leading to the generation of the thiamin pyrimidine from pyridoxine (1) and histidine (6), is proposed. ...

~82%

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Synthesis of suitably protected hydroxymethylene phosphonate...

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