Enzymes in organic synthesis: use of subtilisin and a highly stable mutant derived from multiple site-specific mutations

CH Wong, ST Chen, WJ Hennen, JA Bibbs…

Index: Journal of the American Chemical Society, , vol. 112, # 3 p. 945 - 953

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Citation Number: 173

Abstract

... 8 Present address: Department of Chemistry, The Research Institute of Scripps Clinic, La Jolla, CA 92037. ... initial results encouraged us to study the catalytic properties and the active-site requirements of the ... 0002-7863/90/ 15 I2-945$02.50/0 0 1990 American Chemical Society ...