e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron
Metal-free construction of tricyclic or tetracyclic compounds—acid-promoted synthesis of benzo [4, 5] imidazo [2, 1-a] isoindole and 1, 2-dialkyl-2, 3- …
An environmental friendly, efficient, and easy to operate strategy for synthesizing of benzo [4, 5] imidazo [2, 1-a] isoindole and 1, 2-dialkyl-2, 3-dihydrobenzimidazoles via acid- promoted coupling of dialdehyde and o-diaminobenzene under metal-free conditions is described. A series of products were generated in good yields under mild conditions.