Metal-free construction of tricyclic or tetracyclic compounds—acid-promoted synthesis of benzo [4, 5] imidazo [2, 1-a] isoindole and 1, 2-dialkyl-2, 3- …
An environmental friendly, efficient, and easy to operate strategy for synthesizing of benzo [4, 5] imidazo [2, 1-a] isoindole and 1, 2-dialkyl-2, 3-dihydrobenzimidazoles via acid- promoted coupling of dialdehyde and o-diaminobenzene under metal-free conditions is described. A series of products were generated in good yields under mild conditions.