Tetrahedron letters

Polymer-bound triphenylphosphine as traceless reagent for Mitsunobu reactions in combinatorial chemistry: Synthesis of aryl ethers from phenols and alcohols

AR Tunoori, D Dutta, GI Georg

Index: Tunoori, Ashok Rao; Dutta, Dinah; Georg, Gunda I. Tetrahedron Letters, 1998 , vol. 39, # 48 p. 8751 - 8754

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Citation Number: 103

Abstract

The synthesis of aryl ethers from phenols and alcohols using polymer-bound triphenylphosphine and diethyl azodicar☐ ylate (DEAD) is described. The polymer-bound triphenylphosphines are easily removed by filtration from the reaction products. This method is operationally simple and provides the products with high purity and in good yields.