Synthesis of perfluorinated allylic compounds by radical allylation and their purification over fluorous reverse-phase silica

…, S Kreimerman, T Niguma, S Minakata, M Komatsu…

Index: Ryu, Ilhyong; Kreimerman, Sergio; Niguma, Tatsuro; Minakata, Satoshi; Komatsu, Mitsuo; Luo, Zhiyong; Curran, Dennis P. Tetrahedron Letters, 2001 , vol. 42, # 5 p. 947 - 950

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Citation Number: 47

Abstract

A simple free-radical method for the preparation of a variety of perfluorinated allylic compounds has been developed starting from perfluoroalkyl iodides and allyltins. Allyltributyltin, methallyltributyltin and crotyltributyltin all proved to be useful for the transformation. The desired perfluorinated allylic compound was conveniently isolated from the crude mixture by solid-phase extraction with fluorous reverse-phase silica (FRPS).