Syntheses of fluorous propenes from 3-perfluoroalkyl-2-iodo-1-propanols

C Szíjjártó, P Ivanko, FT Takács, D Szabó…

Index: Szijjarto, Csongor; Ivanko, Peter; Takacs, Ferenc T.; Szabo, Denes; Rabai, Jozsef Journal of Fluorine Chemistry, 2008 , vol. 129, # 5 p. 386 - 389

Full Text: HTML

Citation Number: 4

Abstract

3-(Perfluoroalkyl)-1-propenes are obtained in excellent yields up to 100-g quantities by deiodination–dehydroxylation reactions of the easily accessible 2-iodo-3-(perfluoroalkyl)- propanols with red phosphorus and catalytic amounts of iodine or with an SnCl2/POCl3 reagent pair in pyridine (fluorous Cornforth reaction). Both methods afford fluorous propenes in high GC purity, the former one has high atom-economy and proceeds safely if the ...