Convenient and Regiospecific Method for Synthesis of 4, 5-Diaryl-1-methyl-2-(methylthio)-1 H-imidazole

A Assadieskandar, M Salehi, M Vosooghi…

Index: Assadieskandar, Amir; Salehi, Marjan; Vosooghi, Mohsen; Shafiee, Abbas; Amini, Mohsen Synthetic Communications, 2013 , vol. 43, # 18 p. 2501 - 2507

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Abstract

A convenient, high-yielding, regiospecific synthesis of 1H-imidazole-2-thiones ring has been developed. In addition, a series of 4,5-diaryl-1-methyl-2-(methylthio)-1H-imidazoles 8 were synthesized and characterized. The structure of regioisomers was confirmed through nuclear Overhauser effect spectroscopy and NMR spectroscopy. ... Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free ...