Tetrahedron letters

Reaction of trimethylsilyl derivatives with Meldrum's acid: a new and easy monofunctionalization of malonic acid

B Rigo, D Fasseur, P Cauliez, D Couturier

Index: Rigo, B.; Fasseur, D.; Cauliez, P.; Couturier, D. Tetrahedron Letters, 1989 , vol. 30, # 23 p. 3073 - 3076

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Citation Number: 39

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Treatment of Meldrum's acid with silylated derivatives (amines, lactams or alcohols) yields very easily monofunctionalized malonic silyl esters. Hydrolysis of these silyl esters leads to the corresponding monoacids with a very good yield. ... Methylene dichloride was dried on P 2 O 5 , then ...