Tetrahedron

In situ spectroeletrochemistry and cytotoxic activities of natural ubiquinone analogues

…, H Zhou, YL Ying, DW Li, GR Chen, YT Long, HY Chen

Index: Ma, Wei; Zhou, Hao; Ying, Yi-Lun; Li, Da-Wei; Chen, Guo-Rong; Long, Yi-Tao; Chen, Hong-Yuan Tetrahedron, 2011 , vol. 67, # 33 p. 5990 - 6000

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Citation Number: 15

Abstract

Quinones are a group of potent antineoplastic agents. Here we described effective and facile routes to synthesize a series of ubiquinone analogues (UQAs). These unique compounds have been investigated by electrochemistry and in situ UV–vis spectroelectrochemistry to explore their electron-transfer processes and radical properties in aprotic media. The structure–activities relationships of inhibiting cancer cell proliferation of ...