A highly stereoselective synthesis of anti-HIV 2', 3'-dideoxy-and 2', 3'-didehydro-2', 3'-dideoxynucleosides

JW Beach, HO Kim, LS Jeong, S Nampalli…

Index: Journal of Organic Chemistry, , vol. 57, # 14 p. 3887 - 3894

Full Text: HTML

Citation Number: 87

Abstract

... The organic layer wae washed with brine and sub- sequently dried (NaaO,) and concentrated to dryness ... This material is contained in mauy libraries on microfiche, immediately follows this article in the microfilm version of the journal, and can be ordered from the ACS ... 3888 J. Org ...

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(R)-5-(TERT-BUTYLDIPHENYLSILOXYMETHYL)DIHYDRO-2(3H)FURANONE Structure

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(R)-5-(TERT-BUT...

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Stavudine Structure

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Stavudine

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Stavudine Structure

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Stavudine

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(R)-5-(TERT-BUTYLDIPHENYLSILOXYMETHYL)DIHYDRO-2(3H)FURANONE Structure

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Zalcitabine Structure

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Zalcitabine Structure

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5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-D-erythro-pentonic acid γ-lactone Structure

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Zalcitabine Structure

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Zalcitabine

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126049-67-0

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Zalcitabine Structure

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Zalcitabine

N4-acetyl-1-(5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-β-D-erythro-pentofuranosyl)cytosine Structure

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Zalcitabine Structure

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Stavudine Structure

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Stavudine

1-(5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-β-D-erythro-pentofuranosyl)thymine Structure

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Stavudine Structure

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Stavudine Structure

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1-O-acetyl-5-O-...

~%

2',3'-Dideoxyuridine Structure

5983-09-5

2',3'-Dideoxyuridine

(R)-5-(TERT-BUTYLDIPHENYLSILOXYMETHYL)DIHYDRO-2(3H)FURANONE Structure

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(R)-5-(TERT-BUT...

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2',3'-Dideoxyuridine Structure

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2',3'-Dideoxyuridine

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2',3'-Dideoxyuridine Structure

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2',3'-Dideoxyuridine

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2',3'-Dideoxyuridine Structure

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2',3'-Dideoxyuridine

1-(5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-β-D-erythro-pentofuranosyl)uracil Structure

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2',3'-Dideoxythymidine Structure

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N/A Structure

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~%

2',3'-Dideoxythymidine Structure

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1-O-acetyl-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-2-(phenylselenenyl)-D-erythro-pentafuranose Structure

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1-O-acetyl-5-O-...

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2',3'-Dideoxythymidine Structure

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2',3'-Dideoxyth...

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2',3'-Dideoxythymidine Structure

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2',3'-Dideoxyth...

N/A Structure

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2',3'-Dideoxyinosine Structure

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2',3'-Dideoxyinosine Structure

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2',3'-Dideoxyinosine

1-O-acetyl-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-2-(phenylselenenyl)-D-erythro-pentafuranose Structure

149656-26-8

1-O-acetyl-5-O-...

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2',3'-Dideoxyinosine Structure

69655-05-6

2',3'-Dideoxyinosine

(R)-5-(TERT-BUTYLDIPHENYLSILOXYMETHYL)DIHYDRO-2(3H)FURANONE Structure

102717-29-3

(R)-5-(TERT-BUT...

~%

2',3'-Dideoxyinosine Structure

69655-05-6

2',3'-Dideoxyinosine

N/A Structure

125440-13-3

N/A

~%

2',3'-Dideoxyinosine Structure

69655-05-6

2',3'-Dideoxyinosine

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2',3'-Dideoxyinosine Structure

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2',3'-Dideoxyinosine

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2',3'-Dideoxyinosine Structure

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2',3'-Dideoxyinosine Structure

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