Tetrahedron Letters

Esterification of carboxylic acids catalyzed by in situ generated tetraalkylammonium fluorides

T Ooi, H Sugimoto, K Doda, K Maruoka

Index: Ooi, Takashi; Sugimoto, Hayato; Doda, Kanae; Maruoka, Keiji Tetrahedron Letters, 2001 , vol. 42, # 52 p. 9245 - 9248

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Citation Number: 38

Abstract

Esterification of carboxylic acids with alkyl halides can be efficiently catalyzed by tetrabutylammonium fluoride (TBAF) generated in situ from tetrabutylammonium hydrogensulfate (TBAHSO4) and KF· 2H2O in THF. The general applicability and the characteristic feature of this approach has been amply demonstrated.

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