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Tetrahedron Letters

Esterification of carboxylic acids catalyzed by in situ generated tetraalkylammonium fluorides

T Ooi, H Sugimoto, K Doda, K Maruoka

文献索引:Ooi, Takashi; Sugimoto, Hayato; Doda, Kanae; Maruoka, Keiji Tetrahedron Letters, 2001 , vol. 42, # 52 p. 9245 - 9248

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被引用次数: 38

摘要

Esterification of carboxylic acids with alkyl halides can be efficiently catalyzed by tetrabutylammonium fluoride (TBAF) generated in situ from tetrabutylammonium hydrogensulfate (TBAHSO4) and KF· 2H2O in THF. The general applicability and the characteristic feature of this approach has been amply demonstrated.