Ruthenium-catalyzed S-propargylation of thiols enables the rapid synthesis of propargylic sulfides

…, K Wada, Y Morisaki, T Mitsudo

Index: Kondo, Teruyuki; Morisaki, Yasuhiro; Uenoyama, Shin-Ya; Wada, Kenji; Mitsudo, Take-Aki Journal of the American Chemical Society, 1999 , vol. 121, # 37 p. 8657 - 8658

Full Text: HTML

Citation Number: 41

Abstract

A new and highly efficient catalytic system based on CpRuClL2 is proposed for the S- propargylation of thiols by propargylic carbonates under neutral conditions, in which specific requirements inherent to the different reactivities of aliphatic and aromatic thiols are achieved by tuning both the nature of the ancillary ligand L and the experimental conditions.