The Journal of organic chemistry

Palladium-Catalyzed Selective 2, 3-Diarylation of α, α-Disubstituted 3-Thiophenemethanols via Cleavage of CH and CC Bonds

M Nakano, T Satoh, M Miura

Index: Nakano, Masaya; Satoh, Tetsuya; Miura, Masahiro Journal of Organic Chemistry, 2006 , vol. 71, # 21 p. 8309 - 8311

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Citation Number: 54

Abstract

α, α-Disubstituted 3-thiophenemethanols undergo selective diarylation accompanied by cleavage of the CH and CC bonds of the 2-and 3-positions, respectively, upon treatment with aryl bromides in the presence of a palladium catalyst to give the corresponding 2, 3- ...