Acid-Catalyzed Reactions of Thiophene Nuclei. VIII. Synthesis of Unsymmetrical 2, 3-Diaryl-and 2, 4-Diarylthiophenes Starting from 2, 5-Dichlorothiophene.

…, K Sato, Y Umetsu, A Yoshino, K Takahashi

Index: Sone; Sato; Umetsu; Yoshino; Takahashi Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 8 p. 2187 - 2194

Full Text: HTML

Citation Number: 10

Abstract

Unsymmetrically substituted 2, 4-diaryl-and 2, 3-diarylthiophenes were synthesized from 2, 5- dichlorothiophene via 4-aryl-2-chlorothiophenes in two and four steps including Ni-mediated cross-coupling, respectively. Aluminum chloride-catalyzed reaction of 3-aryl-2- chlorothiophenes with some aromatic ethers unexpectedly led to the formation of the corresponding 2, 4-isomers.