Alixed alkosyforriiic atihydridea (11) of vitrioris peiiic~ illiiis (I j have Ixxii c~ iiverted iiiio the cwrresputidiiig N-arglated 6-arninothioperiirillanic. acids (111) 4 by t reairmelit with SaSII, These penicillin i hioxids have beeii oxidized to the correspoiiding amorphous bis (acg1) disrdfides (IY) by meaiis of iodine, aiid otic represeiitativcb disulfide has beeii described. In general, the penicillin t. hioacids and their wrrespoiidiiig disulfides we poteiil antimicrobial ...
