Tetrahedron

Chemo-enzymatic synthesis of all isomeric 3-phenylserines and-isoserines

H Hönig, P Seufer-Wasserthal, H Weber

Index: Hoenig, H.; Seufer-Wasserthal, P.; Weber, H. Tetrahedron, 1990 , vol. 46, # 11 p. 3841 - 3850

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Citation Number: 64

Abstract

The synthesis of all isomers of 3-phenylserines and 3-phenylisoserines in enantiomerically pure form is presented. Diastereomerically pure educts (threo/erythro-2-azido-3-butanoyoxy- 3-phenyl-propionic esters, threo/erythro-3-azido-2-butanoyloxy-3-phenylpropionic esters, threo-2-butanoylamino-3-butanoyloxy-3-phenylpropionic ester, erythro-3-butanoylamino-2- butanoyloxy-3-phenyl-propionamide) were prepared from cinnamic acid derivatives or via ...

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