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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Organic letters

Steric Control of Site Selectivity in the Pd-Catalyzed C–H Acetoxylation of Simple Arenes

AK Cook, MH Emmert, MS Sanford

Index: Organic Letters, , vol. 15, # 21 p. 5428 - 5431

Full Text: HTML

Citation Number: 28

Abstract

... Volume: Page ... Organic Letters. ... large increases in yield and enhancements in selectivity for acetoxylation at the sterically less hindered 4-position.(14) Under these conditions, the best selectivity was obtained with acridine as the ligand (1A:1B = 5:95, entry 8).(15). ...

 Related Synthetic Route
5-Iodo-2,4,6-trimethyl-1,3-phenylene diacetate Structure

33035-41-5

5-Iodo-2,4,6-tr...

Anisole Structure

100-66-3

Anisole

~%

Guaiacol acetate Structure

613-70-7

Guaiacol acetate

p-Acetoxyanisole Structure

1200-06-2

p-Acetoxyanisole

Detail Learn More
(Diacetoxyiodo)benzene Structure

3240-34-4

(Diacetoxyiodo)...

Anisole Structure

100-66-3

Anisole

~%

Guaiacol acetate Structure

613-70-7

Guaiacol acetate

p-Acetoxyanisole Structure

1200-06-2

p-Acetoxyanisole

Detail Learn More
(Diacetoxyiodo)benzene Structure

3240-34-4

(Diacetoxyiodo)...

Benzotrifluoride Structure

98-08-8

Benzotrifluoride

~%

4-(Trifluoromethyl)phenyl acetate Structure

78950-29-5

4-(Trifluoromet...

3-(TRIFLUOROMETHYL)PHENYL ACETATE Structure

78950-34-2

3-(TRIFLUOROMET...

Learn More
5-Iodo-2,4,6-trimethyl-1,3-phenylene diacetate Structure

33035-41-5

5-Iodo-2,4,6-tr...

Chlorobenzene Structure

108-90-7

Chlorobenzene

~%

4-CHLOROPHENOL ACETATE Structure

876-27-7

4-CHLOROPHENOL ...

3-CHLOROPHENYLACETATE Structure

13031-39-5

3-CHLOROPHENYLA...

Learn More
(Diacetoxyiodo)benzene Structure

3240-34-4

(Diacetoxyiodo)...

Benzotrifluoride Structure

98-08-8

Benzotrifluoride

~%

4-(Trifluoromethyl)phenyl acetate Structure

78950-29-5

4-(Trifluoromet...

3-(TRIFLUOROMETHYL)PHENYL ACETATE Structure

78950-34-2

3-(TRIFLUOROMET...

Learn More
N/A Structure

253185-03-4

N/A

5-Iodo-2,4,6-trimethyl-1,3-phenylene diacetate Structure

33035-41-5

5-Iodo-2,4,6-tr...

~%

Phenol,4-(1,1-dimethylethyl)-, 1-acetate Structure

3056-64-2

Phenol,4-(1,1-d...

acetic acid,3-tert-butylphenol Structure

13189-51-0

acetic acid,3-t...

Learn More
N/A Structure

253185-03-4

N/A

(Diacetoxyiodo)benzene Structure

3240-34-4

(Diacetoxyiodo)...

~%

Phenol,4-(1,1-dimethylethyl)-, 1-acetate Structure

3056-64-2

Phenol,4-(1,1-d...

acetic acid,3-tert-butylphenol Structure

13189-51-0

acetic acid,3-t...

Learn More
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Detail Synthetic Route


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