Fe-Catalyzed Regiodivergent [1, 2]-Shift of α-Aryl Aldehydes

A Gutiérrez-Bonet, A Flores-Gaspar…

Index: Gutierrez-Bonet, Alvaro; Flores-Gaspar, Areli; Martin, Ruben Journal of the American Chemical Society, 2013 , vol. 135, # 34 p. 12576 - 12579

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Citation Number: 14

Abstract

An Fe-catalyzed conversion of aldehydes to ketones via [1, 2]-shift has been developed. This skeletal rearrangement shows a wide substrate scope and chemoselectivity profile while exhibiting an excellent [1, 2]-aryl or [1, 2]-alkyl shift selectivity that is easily switched by electronic effects.