Chemische Berichte

o??(α??Benzotriazolylalkyl) phenols: Versatile Intermediates for the Synthesis of Substituted Phenols

AR Katritzky, X Lan, JN Lam

Index: Katritzky, Alan R.; Lan, Xiangfu; Lam, Jamshed N. Chemische Berichte, 1991 , vol. 124, # 8 p. 1809 - 1817

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Citation Number: 47

Abstract

Abstract Phenols and naphthols are benzotriazolylmethylated by 1-(hydroxymethyl)-1H- benzotriazole (13)(a formaldehyde derivative) in the o-or (if both o-positions are occupied) in the p-position. The reaction can be extended to other aldehydes in the case of the naphthols. The methylene group in the o-(benzotriazolylmethyl) phenols can be lithiated (but only after trimethylsilyl protection of the hydroxy group) and then substituted by various ...

~87%

~49%

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