Journal of organometallic chemistry

Cross-coupling reactions with boronic acids in water catalysed by oxime-derived palladacycles

L Botella, C Nájera

Index: Botella, Luis; Najera, Carmen Journal of Organometallic Chemistry, 2002 , vol. 663, # 1-2 p. 46 - 57

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Citation Number: 201

Abstract

Palladacycles derived from phenone-oximes 1 are efficient precatalysts for the Suzuki– Miyaura coupling of arylboronic acids with aromatic and heteroaromatic bromides and chlorides under water reflux under aerobic conditions. Alternatively, the coupling can also be carried out at room temperature in methanol–water. Aryl bromides gave biaryls with TON up to 105 and TOF up to 7× 104 h− 1. Activated and deactivated aryl chlorides need the ...