A practical and versatile approach toward a one-pot synthesis of 2, 3-disubstituted 4 (3H)-quinazolinones

…, P Salehi, M Bahramnejad, M Alizadeh

Index: Dabiri, Minoo; Salehi, Peyman; Bahramnejad, Mahboobeh; Alizadeh, Mohsen Monatshefte fur Chemie, 2010 , vol. 141, # 8 p. 877 - 881

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Citation Number: 22

Abstract

Abstract An effective one-pot three-component route to 4 (3 H)-quinazolinones from commercially available starting materials is reported. Thus, isatoic anhydride reacted with ammonium acetate or primary amines and aldehydes in the presence of iodine to produce the corresponding quinazolinone derivatives in moderate to good yields. Graphical Abstract