Attempted cyclization of an epoxide. Elimination of an epoxide

I Rothberg, L Schneider, S Kirsch…

Index: Rothberg, Irvin; Schneider, Louis; Kirsch, Sheldon; OFee, Robert Journal of Organic Chemistry, 1982 , vol. 47, # 13 p. 2675 - 2676

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Citation Number: 3

Abstract

Nv. 5 7 tetrahydrofuran. GLC examination of the products showed a complex mixture of 15 different compounds. None was present as a major component. There was no cyclohexanol or cyclopentylmethanol produced, which would have been the expected cyclization products. Clearly, for cyclization to occur there are very severe restrictions on the geometry of the chloro epoxide. We investigated whether the chloromethylene group must be ...