The 1, 3-Rearrangement. The Synthesis and Rearrangement of 4, 4-Dimethyl-3-ethyl-2-pentanol1a

WA Mosher, JC Cox Jr

Index: Mosher; Cox Journal of the American Chemical Society, 1950 , vol. 72, p. 3701,3703

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Citation Number: 12

Abstract

3. A possible course for the condensations has been suggested. The proposed mechanism assumes that two consecutive reactions occur, ie, an elimination reaction between the ketone anion and 0-chloropropionitrile to give the ketone and acylonitrile, which then undergo a Michael condensation to give the cyanoethylated derivatives.