Potassium fluoride assisted derivatization of carboxylic acids to phenacyl esters for determination by high-performance liquid chromatography

JM Miller, ID Brindle, SR Cater, KH So…

Index: Miller, Jack M.; Brindle, Ian D.; Cater, Stephen R.; So, Kwok-Hung; Clark, James H. Analytical Chemistry, 1980 , vol. 52, # 14 p. 2430 - 2432

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Citation Number: 14

Abstract

Phenacyl esters of carboxylic acids have become increasingly important recently because of their sensitivity to detection in high-performance liquid chromatographs. Since traditional procedures have inherent problems such as slowness of reaction (I) and variable products (2), which have not lent themselves to exploitation, newer methods of derivatization have emerged.